Antioxidant, analgesic and anti-inflammatory activities of the methanolic extract of Piper betle leaves

Authors

  • Badrul Alam Department of Pharmacy, Atish Dipankar University of Science & Technology, Dhaka, Bangladesh
  • Fahima Akter Department of Pharmacy, Atish Dipankar University of Science & Technology, Dhaka, Bangladesh
  • Jesmin Chowdhury Department of Pharmacy, Atish Dipankar University of Science & Technology, Dhaka, Bangladesh
  • Kazi Sifath-E-Jahan Department of Pharmacy, Atish Dipankar University of Science & Technology, Dhaka, Bangladesh
  • Nahida Parvin Department of Pharmacy, Atish Dipankar University of Science & Technology, Dhaka, Bangladesh
  • Rashna Sharmin Pia Department of Pharmacy, Atish Dipankar University of Science & Technology, Dhaka, Bangladesh
  • Sharmin Akter Department of Pharmacy, Atish Dipankar University of Science & Technology, Dhaka, Bangladesh
Abstract:

Objective:The present study was designed to evaluate the antioxidant, analgesic, and anti-inflammatory activities ofthe methanolic extract of Piper betle leaves (MPBL). Materials and Methods: MPBL was evaluated for anti-inflammatory activity using carrageenan-induced hind paw edema model. Analgesic activity of MPBL was evaluated by hot plate, writhing, and formalin tests. Total phenolic and flavonoids content, total antioxidant activity, scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, peroxynitrate (ONOO-) as well as  inhibition of total ROS generation, and assessment of reducing power were used to evaluate antioxidant potential of MPBL. Results: The extract of MPBL, at the dose of 100 and 200 mg/kg, produced a significant (p

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

antioxidant, analgesic and anti-inflammatory activities of the methanolic extract of piper betle leaves

objective:the present study was designed to evaluate the antioxidant, analgesic, and anti-inflammatory activities ofthe methanolic extract of piper betle leaves (mpbl). materials and methods: mpbl was evaluated for anti-inflammatory activity using carrageenan-induced hind paw edema model. analgesic activity of mpbl was evaluated by hot plate, writhing, and formalin tests. total phenolic and fla...

full text

Analgesic and anti-inflammatory activities of Zea mays leaves

Background & Aim:Zea mays leaf used traditionally in Ibibio ethno medicine in Southern Nigeria to treat malaria and other inflammatory diseases. These anti-inflammatory and analgesic properties were evaluated against experimentally induced inflammation and pains using standard models. Experimental: The effects of ethanol leaf extract of Zea mays <...

full text

Analgesic and anti-inflammatory activities of Zea mays leaves

Background & Aim:Zea mays leaf used traditionally in Ibibio ethno medicine in Southern Nigeria to treat malaria and other inflammatory diseases. These anti-inflammatory and analgesic properties were evaluated against experimentally induced inflammation and pains using standard models. Experimental: The effects of ethanol leaf extract of Zea mays <...

full text

Antimalarial activity of methanolic leaf extract of Piper betle L.

The need for new compounds active against malaria parasites is made more urgent by the rapid spread of drug-resistance to available antimalarial drugs. The crude methanol extract of Piper betle leaves (50-400 mg/kg) was investigated for its antimalarial activity against Plasmodium berghei (NK65) during early and established infections. The phytochemical and antioxidant potentials of the crude e...

full text

Anti-inflammatory and anti-nociceptive activities of methanolic extract of the leaves of Fraxinus floribunda Wallich.

Fraxinus floribunda Wallich (Family-Oleaceae) is a wide green tree in the sub-alpine region of Sikkim, India. The methanolic extract of the leaves of Fraxinus floribunda (MEFF) at 100, 200 and 400 mg/kg/p.o was screened in rats for anti-inflammatory activity by acute-carrageenan induced paw edema, sub-acute cotton pellet induced granuloma and chronic Freund's adjuvant induced arthritis models. ...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 3  issue 2

pages  112- 125

publication date 2013-03-01

{@ msg @}

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023